China (Mainland)
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Newblue (Z)-Guggulsterone CAS NO.95975-55-6
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,
- Product Details
Keywords
- (Z)-Guggulsterone
- 95975-55-6
- TIANFU (Z)-Guggulsterone
Quick Details
- ProName: Newblue (Z)-Guggulsterone
- CasNo: 95975-55-6
- Molecular Formula: C21H28O2
- Appearance: Solid
- Application: Intermediates
- DeliveryTime: as client's demand quantity
- PackAge: as requested
- Port: SHANGHAI
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 98% min
- Storage: room temperature
- Transportation: by sea, by air or by courier
- LimitNum: 1 Kilogram
Superiority
Details
(Z)-Guggulsterone Basic information
Product Name: (Z)-Guggulsterone
Synonyms: CIS-4,17(20)-PREGNADIENE-3,16-DIONE;CIS GUGGULSTERONE;GUGULSTERONE;GUGGULSTERONE Z;GUGGULSTERONE (Z FORM);GUGGULESTERONE Z;GUGGULSTERONE;4,17(20)-(CIS)-PREGNADIEN-3,16-DIONE
CAS: 95975-55-6
MF: C21H28O2
MW: 312.45
EINECS:
Product Categories: Miscellaneous
Mol File: 95975-55-6.mol
(Z)-Guggulsterone Structure
(Z)-Guggulsterone Chemical Properties
storage temp. 2-8°C
solubility DMSO: 5 mg/mL
form powder
color light yellow
CAS DataBase Reference 95975-55-6(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 37
Safety Statements 36
WGK Germany 3
(Z)-Guggulsterone Usage And Synthesis
Biological Activity Broad spectrum steroid receptor ligand; binds with high affinity to mineralocorticoid receptors (K i = 39 nM) and lower affinity to progesterone, androgen and glucocorticoid receptors (K i values are 201, 240 and 224 nM respectively). Functions primarily as an antagonist of these receptors, with the exception of the progesterone receptor where it displays partial agonist effects. Also exerts hypolipidemic activity, likely via antagonism of the receptor for bile acids (farnesoid X receptor; FXR).