- Product Details
Keywords
- 938440-64-3
- KU-0063794
- KU-0063794
Quick Details
- ProName: KU-0063794 938440-64-3
- CasNo: 938440-64-3
- Molecular Formula: C25H31N5O4
- Appearance: white powder
- Application: For organic use
- DeliveryTime: PROMPT
- PackAge: as clients needs
- Port: Shanghai port
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99.0%
- Storage: Room temperature
- Transportation: AS PER MSDS
- LimitNum: 1 Kilogram
- Heavy metal: N/A
- Grade: Industrial Grade,Pharma Grade
- N/A: N/A
Superiority
KU-0063794 Basic information |
Product Name: | KU-0063794 |
Synonyms: | BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-2-METHOXY-, REL-;KU0063794;5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;(5-(2-((2R,6S)-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol;rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;KU0063794(KU63794);KU-0063794(KU 0063794);BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7 |
CAS: | 938440-64-3 |
MF: | C25H31N5O4 |
MW: | 465.551 |
EINECS: | |
Product Categories: | Inhibitors |
Mol File: | 938440-64-3.mol |
KU-0063794 Chemical Properties |
density | 1.248 |
storage temp. | Store at RT |
KU-0063794 Usage And Synthesis |
Biological Activity | Selective inhibitor of mammalian target of rapamycin (mTOR) (IC 50 ~10 nM for mTORC1 and mTORC2 respectively). Displays no activity at PI 3-kinase or 76 other kinases tested. Inhibits activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK. Suppresses cell growth and induces G 1 cell cycle arrest in vitro . |
Details
KU-0063794 Basic information |
Product Name: | KU-0063794 |
Synonyms: | BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-2-METHOXY-, REL-;KU0063794;5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;(5-(2-((2R,6S)-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol;rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;KU0063794(KU63794);KU-0063794(KU 0063794);BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7 |
CAS: | 938440-64-3 |
MF: | C25H31N5O4 |
MW: | 465.551 |
EINECS: | |
Product Categories: | Inhibitors |
Mol File: | 938440-64-3.mol |
KU-0063794 Chemical Properties |
density | 1.248 |
storage temp. | Store at RT |
KU-0063794 Usage And Synthesis |
Biological Activity | Selective inhibitor of mammalian target of rapamycin (mTOR) (IC 50 ~10 nM for mTORC1 and mTORC2 respectively). Displays no activity at PI 3-kinase or 76 other kinases tested. Inhibits activation and hydrophobic motif phosphorylation of Akt, S6K and SGK, but not RSK. Suppresses cell growth and induces G 1 cell cycle arrest in vitro . |