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NewblueCHEM--93479-97-1---Glimepiride CAS NO.93479-97-1
- FOB Price: USD: 500.00-500.00 /Metric Ton Get Latest Price
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,T/T
- Available Specifications:
1(1-2)Metric Ton
- Product Details
Keywords
- TIANFUCHEM--93479-97-1---Glimepiride
- TIANFUCHEM--93479-97-1---Glimepiride
- TIANFUCHEM--93479-97-1---Glimepiride
Quick Details
- ProName: NewblueCHEM--93479-97-1---Glimepiride
- CasNo: 93479-97-1
- Molecular Formula: C24H34N4O5S
- Appearance: white powder
- Application: Pharmaceutical intermediates
- DeliveryTime: in stock
- PackAge: bag
- Port: China main port
- ProductionCapacity: 1 Metric Ton/Day
- Purity: 99%
- Storage: Room temperature
- Transportation: by sea
- LimitNum: 1 Metric Ton
- Heavy metal: N/A
- Grade: Industrial Grade
- Transportation: N/A
Superiority
Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:
1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
Our advantage:
1. Higest quality and good package
2.Fast delivery
3.Better payment term
4.Fast response to customer within 6 hours
5.Good business credit in Europe ,US ,Japan ,Korea
Anyway ,if you need any chemicals from China ,Henan Newblue can help you
Details
Product Name:GlimepirideSynonyms:AMARYL;3-ETHYL-2,5-DIHYDRO-4-METHYL-N-[2-[4-[[[[(TRANS-4-METHYLCYCLOHEXYL)AMINO]CARBONYL]AMINO]SULFONYL]PHENYL]ETHYL]-2-OXO-1H-PYRROLE-1-CARBOXAMIDE;3-ETHYL-2,5-DIHYDRO-4-METHYL-N-[2-[4-[[[[(TRANS-4-METHYLCYCLOHEXYL)AMINO]CARBONYL]AMINO]SULFONYL]PHENYL]ETHYL]-2-OXO-1H-PYRROLE-1-CARBOXYAMIDE;Gliclazide(diamicron);CLIMEPIRIDE;Glimpiride;3-Ethyl-2,5-dihydro-4-methyl-N-[2-[4-[[[[trans-4-methylcyclohexyl)amino]carbonyl]amino]sulfonyl]phenyl]ethyl]-2-oxo-1H-pyrrole-1-carboxyamide;1H-Pyrrole-1-carboxamide, 3-ethyl-2,5-dihydro-4-methyl-N-2-4-(trans-4-methylcyclohexyl)aminocarbonylaminosulfonylphenylethyl-2-oxo-CAS:93479-97-1MF:C24H34N4O5SMW:490.62EINECS:Product Categories:Active Pharmaceutical Ingredients;APIs;Intermediates & Fine Chemicals;Pharmaceuticals;Monovalent Ion Channels;Potassium Channel Modulators;Voltage-gated Ion Channels;API's;Chiral Reagents;Heterocycles;Sulfur & Selenium Compounds;API;NEURONTIN;Diabetes ResearchMol File:93479-97-1.mol
Glimepiride Chemical Properties
Melting point 212.2-214.5 °C
storage temp. Room tempsolubility DMSO: >10 mg/mL
form solid
color white
Merck 14,4440CAS DataBase Reference93479-97-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,XiRisk Statements 21-36/38-46-62-63Safety Statements 25-26-36/37-53WGK Germany 3
RTECS UX9363950
MSDS Information
ProviderLanguageAmaryEnglishSigmaAldrichEnglish
Glimepiride Usage And Synthesis
DescriptionGlimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug. It is sometimes classified as either the first third-generation sulfonylurea, or as second-generation. Like all sulfonylureas, glimepiride acts as an insulin secretagogue. It lowers blood sugar by stimulating the release of insulin from functioning pancreatic beta cells and by increasing sensitivity of peripheral tissues to insulin. Glimepiride likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin. Glimepiride is mainly used to treat patients with type 2 diabetes and can also decrease the chances that someone will develop complications of type 2 diabetes, such as kidney damage, blindness, nerve problems, loss of limbs, sexual function problems and heart attack or stroke. The drug was approved by the FDA in 1995 and is manufactured by Sanofi-Aventis. It can be used along with proper diet and exercise program and may also be used alone or with other antidiabetic medicines if need. The drug is available only with your doctor's prescription.References1. #;
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9. #;PropertiesWhite Cyrstalline SolidUsesanticonvulsantUsesFor concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.UsesA sulfonylurea hypoglycemic agent. Used as an antidiabeticBiological ActivityPotent K ATP channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac K ATP channels with an IC 50 of 6.8 nM.
Glimepiride Chemical Properties
Melting point 212.2-214.5 °C
storage temp. Room tempsolubility DMSO: >10 mg/mL
form solid
color white
Merck 14,4440CAS DataBase Reference93479-97-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn,XiRisk Statements 21-36/38-46-62-63Safety Statements 25-26-36/37-53WGK Germany 3
RTECS UX9363950
MSDS Information
ProviderLanguageAmaryEnglishSigmaAldrichEnglish
Glimepiride Usage And Synthesis
DescriptionGlimepiride (original trade name Amaryl) is an orally available medium-to-long-acting sulfonylurea antidiabetic drug. It is sometimes classified as either the first third-generation sulfonylurea, or as second-generation. Like all sulfonylureas, glimepiride acts as an insulin secretagogue. It lowers blood sugar by stimulating the release of insulin from functioning pancreatic beta cells and by increasing sensitivity of peripheral tissues to insulin. Glimepiride likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Membrane depolarization stimulates calcium ion influx through voltage-sensitive calcium channels. This increase in intracellular calcium ion concentration induces the secretion of insulin. Glimepiride is mainly used to treat patients with type 2 diabetes and can also decrease the chances that someone will develop complications of type 2 diabetes, such as kidney damage, blindness, nerve problems, loss of limbs, sexual function problems and heart attack or stroke. The drug was approved by the FDA in 1995 and is manufactured by Sanofi-Aventis. It can be used along with proper diet and exercise program and may also be used alone or with other antidiabetic medicines if need. The drug is available only with your doctor's prescription.References1. #;
2. #;
3. #
4. #
5. #
6. #
7. # docId=d03864a1
8. #
9. #;PropertiesWhite Cyrstalline SolidUsesanticonvulsantUsesFor concomitant use with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus.UsesA sulfonylurea hypoglycemic agent. Used as an antidiabeticBiological ActivityPotent K ATP channel blocker and anti-diabetic agent. Inhibits pinacidil-activated cardiac K ATP channels with an IC 50 of 6.8 nM.