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Product Name: Manidipine
Synonyms: 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl]5-methyl ester;Manidipine;Manidipine(CV-4093);2-(4-Diphenylmethyl-1-piperazinyl)ethyl methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate;3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(4-(diphenylmethyl)-1-piperazinyl)ethyl methyl ester;2-(4-(Diphenylmethyl)-1-piperazinyl)ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate;89226-75-5 (Di-hydrochloride);1-diphenylmethyl-4-(2-hydroxyethyl)piperazine
CAS: 89226-50-6
MF: C35H38N4O6
MW: 610.7
EINECS: 1806241-263-5
Product Categories: Dihydropyridine;Artedil, Iperten;Inhibitors;Dihydropyridine Class Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 89226-50-6.mol
Manidipine Structure
Manidipine Chemical Properties
Melting point  125-128°C
Boiling point  722.0±60.0 °C(Predicted)
density  1.232±0.06 g/cm3(Predicted)
storage temp.  -20°C Freezer
pka 6.12±0.10(Predicted)
Safety Information
MSDS Information
Manidipine Usage And Synthesis
Chemical Properties Light Yellow Crystalline Solid
Uses A dihydropyridine calcium channel blocker. Antihypertensive
Uses Manidipine (Manyper) is a lipophilic, third-generation, highly vasoselective dihydropyridine calcium antagonist with an IC50 of 2.6 nM. It causes systemic vasodilation by inhibiting the voltage-dependent calcium inward currents in smooth muscle cells. It