879085-55-9 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide CAS NO.879085-55-9
- FOB Price: USD: 1,000.00-1,000.00 /Metric Ton Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,T/T
- Available Specifications:
pharma(0-1)Metric Ton
- Product Details
Keywords
- 879085-55-9
- 2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide
- C19H14Cl2N2O3S
Quick Details
- ProName: 879085-55-9 2-Chloro-N-[4-chloro-3-(2-...
- CasNo: 879085-55-9
- Molecular Formula: C19H14Cl2N2O3S
- Appearance: white powder
- Application: pharma
- DeliveryTime: prompt
- PackAge: as clients needs
- Port: Shanghai,QingdaoTianjin,Guangzhou
- ProductionCapacity: 1 Metric Ton/Day
- Purity: 99%
- Storage: RT
- Transportation: sea
- LimitNum: 1 Kilogram
- Moisture Content: N/A
- Impurity: N/A
- N/A: N/A
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Details
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide Chemical Properties
density 1.440
Safety Information
MSDS Information
2-Chloro-N-[4-chloro-3-(2-pyridinyl)phenyl]-4-(methylsulfonyl)benzamide Usage And Synthesis
Chemical Properties White Solid
Uses Targets the Hedgehog (Hh) pathway. Inhibition of the Hh signaling may be effective in the treatment and prevention of many types of human cancers.
Uses Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM.
Definition ChEBI: A benzamide obtained by formal condensation between the carboxy group of 2-chloro-4-(methylsulfonyl)benzoic acid and the anilino group of 4-chloro-3-(pyridin-2-yl)aniline. Used for the treatment metastatic basal cell carcinoma.