Our company was built in 2009 with an ISO certificate.

In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.

Our main business covers the fields below:

1.Noble Metal Catalysts (Pt.Pd...)

2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

3.OLED intermediates (Fluorene,Carbazole,Boric acid...)

4.Customs Synthesis

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Isradipine Basic information
Product Name: Isradipine
Synonyms: PN-200-110;Presca;Prescal;4-(4-Benzofurazanyl)-2，6-dimethyl-1，4-dihydro-3，5-pyridinedicarboxylic acid methyl 1-methylethyl ester;Dynacrine;Iomir;Rebfiden;3,5-Pyridinedicarboxylic acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, methyl 1-methylethyl ester
CAS: 75695-93-1
MF: C19H21N3O5
MW: 371.39
EINECS:
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Calcium channel;Ion Channels;ALLEGRA
Mol File: 75695-93-1.mol
Isradipine Structure
Isradipine Chemical Properties
Melting point  166-1680C
storage temp.  2-8°C
solubility  DMSO: ~26 mg/mL
form  solid
color  yellow
CAS DataBase Reference 75695-93-1(CAS DataBase Reference)
NIST Chemistry Reference Isradipine(75695-93-1)
Safety Information
Safety Statements  22-24/25
WGK Germany  3

Isradipine Usage And Synthesis
Chemical Properties Yellow Solid
Uses Dihydropyridine calcium channel blocker. Antihypertensive; antianginal
Uses nonsedating H1-antihistamine
Biological Activity Potent and selective L-type voltage-gated Ca 2+ channel blocker. EC 50 and pA 2 values are 1.4 nM and 10.3 for relaxation of depolarization- and Ca 2+ -induced contractions of rabbit aorta respectively; EC 25 = 0.45 nM for reduction in rate of spontaneously beating guinea pig right atria. Long-acting antihypertensive agent in vivo , exerting primary effects on vascular tissue with secondary negative chronotropic action.