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Product Name: N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
Synonyms: 4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid N-succinimidyl ester;LKA;N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate, SMCC;SMCC [4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester];trans-4-(Maleimidomethyl)-cyclohexane carboxylic acid-NHS ester;SMCC N-SucciniMidyl 4-(N-MaleiMidoMethyl)cyclohexane-1-carboxylate;N-SucciniMidyl 4-(N-MaleiMidoMethyl)cyclohexanecarboxylate;4-(N-MaleiMidoMethyl)cyclohexane-1-carboxylic acid N-hydroxysucciniMide ester, 98+%
CAS: 64987-85-5
MF: C16H18N2O6
MW: 334.32
EINECS: 1592732-453-0
Product Categories: Heterobifunctional Crosslinker;heteroXlink;Maleimide Derivatives;Cross Linking Reagents;MTS & Sulfhydryl Active Reagents
Mol File: 64987-85-5.mol
N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Structure
N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Chemical Properties
Melting point  180-182 °C(lit.)
Boiling point  501.7±42.0 °C(Predicted)
density  1.42±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL
form  powder
pka -2.24±0.20(Predicted)
Sensitive  Moisture & Light Sensitive
BRN  1555271
CAS DataBase Reference 64987-85-5(CAS DataBase Reference)
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-60-37
WGK Germany  3
F  10-21
HS Code  29280000
MSDS Information
Provider Language
SigmaAldrich English
N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate Usage And Synthesis
Chemical Properties White Crystalline Solid
Uses A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. It conjugates anti-digoxin F(ab’)2 fragments to -galactosidase. Conjugates hIgG to alkaline phosphatase. Spacer Arm: 11.6 Angstroms
Definition ChEBI: An N-hydroxysuccinimide ester derived from 4-(N-maleimidomethyl)cyclohexane-1-carboxylic acid.