Furacilin Basic information
Product Name: Furacilin
Synonyms: NFZ;NITROFURAL;NITROFURAZONE;(5-Nitro-2-furfurylidenamino)urea;(5-Nitro-2-furfurylideneamino)urea;1-(5-Nitro-2-furfurylidene)semicarbazide;1-(5-Nitrofurfurylidene)semicarbazide;2-((5-nitro-2-furanyl)methylene)-hydrazinecarboxamid
CAS: 59-87-0
MF: C6H6N4O4
MW: 198.14
EINECS: 200-443-1
Product Categories: Furan&Benzofuran;NA - NIAntibiotics;Alphabetic;Chemical Structure;N;Others;Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Pharmaceutical intermediate;ACTIN-N
Mol File: 59-87-0.mol
Furacilin Structure
Furacilin Chemical Properties
Melting point 242-244 °C(lit.)
Fp 2 °C
storage temp. 2-8°C
Water Solubility <0.1 g/100 mL at 19 ºC
Sensitive Light Sensitive
Merck 14,6600
BRN 86403
InChIKey IAIWVQXQOWNYOU-FPYGCLRLSA-N
CAS DataBase Reference 59-87-0(CAS DataBase Reference)
NIST Chemistry Reference 5-Nitro furfural semicarbazone(59-87-0)
EPA Substance Registry System Hydrazinecarboxamide, 2-[(5-nitro-2-furanyl)methylene]- (59-87-0)
Safety Information
Hazard Codes Xn,F
Risk Statements 22-36-20/21/22-11
Safety Statements 36-36/37-26-16
RIDADR 3249
WGK Germany 3
RTECS LT7700000
F 8
TSCA Yes
HazardClass 6.1(b)
PackingGroup III
Hazardous Substances Data 59-87-0(Hazardous Substances Data)
Furacilin Usage And Synthesis
Chemical Properties white to light yellow crystal powde
Uses Anti-infective (topical). Antimicrobial.
Definition ChEBI: A semicarbazone resulting from the formal condensation of semicarbazide with 5-nitrofuraldehyde. A broad spectrum antibacterial drug, although with little activity against Pseudomonas species, it is used as a local application for burns, ulcer , wounds and skin infections.
General Description Odorless pale yellow needles or yellow powder. pH (saturated aqueous solution) 6.0 - 6.5. Alkaline solutions are dark orange.
Air & Water Reactions Insoluble in water.
Reactivity Profile Furacilin darkens on prolonged exposure to light. Furacilin can react violently with reducing materials. .
Fire Hazard Flash point data for Furacilin are not available; however, Furacilin is probably combustible.
Furacilin Preparation Products And Raw materials
Raw materials Acetic anhydride-->Urea-->Hydrazinium hydroxide-->5-Nitrofurfural