Product Name: Chrysophanic acid
Synonyms: Chrysophanic acid 481-74-3;CHRYSOPHANOL:9,10-ANTHRACENEDIONE,1,8-DIHYDROXY-3-METHYL;Natural Yellow 23.;CHRYSOPHANOL(SH);9,10-ANTHRACENEDIONE,1,8-;CHRYSOPHANIC ACID hplc;CHRYSOPHANOL WITH HPLC;1,8-dihydroxy-3-methyl-anthracene-9,10-dione
CAS: 481-74-3
MF: C15H10O4
MW: 254.24
EINECS: 207-572-2
Product Categories: Anthraquinones, Hydroquinones and Quinones;The group of Polydatin;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Aloe Vera;Bioactive Small Molecules;Building Blocks;C15 to C38;Carbonyl Compounds;Cell Biology;Chemical Synthesis;DIG-DY;Ketones;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 481-74-3.mol

Chrysophanic acid Chemical Properties
Melting point  194-198 °C
Boiling point  357.45°C (rough estimate)
density  1.2693 (rough estimate)
refractive index  1.4872 (estimate)
storage temp.  2-8°C
solubility  chloroform: soluble1%
pka 6.63±0.20(Predicted)
form  crystalline
color  yellow-orange
Water Solubility  <0.1 g/100 mL at 18 ºC
λmax 429nm(MeOH)(lit.)
Merck  14,2258
BRN  1252300
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 481-74-3(CAS DataBase Reference)
EPA Substance Registry System Chrysophanic acid (481-74-3)

Safety Information
Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  CB6725000
F  8-10
HS Code  29146990

Chrysophanic acid Usage And Synthesis
Chemical Properties yellow crystalline solid or brown powder
Uses Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Uses antineoplastic, antibacterial
Uses A topical ointment used in the treatment of dermal conditions such as eczema and herpes.
Definition ChEBI: A trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity.
General Description Golden yellow plates or brown powder. Melting point 196°C. Slightly soluble in water. Pale yellow aqueous solutions turn red on addition of alkali. Solutions in concentrated sulfuric acid are red.
Air & Water Reactions Insoluble in water.
Reactivity Profile Chrysophanic acid is incompatible with strong oxidizing agents.
Fire Hazard Flash point data for Chrysophanic acid are not available; however, Chrysophanic acid is probably combustible.

Product Name: Chrysophanic acid
Synonyms: Chrysophanic acid 481-74-3;CHRYSOPHANOL:9,10-ANTHRACENEDIONE,1,8-DIHYDROXY-3-METHYL;Natural Yellow 23.;CHRYSOPHANOL(SH);9,10-ANTHRACENEDIONE,1,8-;CHRYSOPHANIC ACID hplc;CHRYSOPHANOL WITH HPLC;1,8-dihydroxy-3-methyl-anthracene-9,10-dione
CAS: 481-74-3
MF: C15H10O4
MW: 254.24
EINECS: 207-572-2
Product Categories: Anthraquinones, Hydroquinones and Quinones;The group of Polydatin;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Aloe Vera;Bioactive Small Molecules;Building Blocks;C15 to C38;Carbonyl Compounds;Cell Biology;Chemical Synthesis;DIG-DY;Ketones;Nutrition Research;Organic Building Blocks;Phytochemicals by Plant (Food/Spice/Herb);chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 481-74-3.mol

Chrysophanic acid Chemical Properties
Melting point  194-198 °C
Boiling point  357.45°C (rough estimate)
density  1.2693 (rough estimate)
refractive index  1.4872 (estimate)
storage temp.  2-8°C
solubility  chloroform: soluble1%
pka 6.63±0.20(Predicted)
form  crystalline
color  yellow-orange
Water Solubility  <0.1 g/100 mL at 18 ºC
λmax 429nm(MeOH)(lit.)
Merck  14,2258
BRN  1252300
Stability: Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 481-74-3(CAS DataBase Reference)
EPA Substance Registry System Chrysophanic acid (481-74-3)

Safety Information
Hazard Codes  Xi
Risk Statements  36/38-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  CB6725000
F  8-10
HS Code  29146990

Chrysophanic acid Usage And Synthesis
Chemical Properties yellow crystalline solid or brown powder
Uses Chrysophanic acid, a natural anthraquinone, is used to study anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells 1. It is also used to study the inhibition of replication of poliovirus types 2 and 3 (Picornaviridae) in vitro 2.
Uses antineoplastic, antibacterial
Uses A topical ointment used in the treatment of dermal conditions such as eczema and herpes.
Definition ChEBI: A trihydroxyanthraquinone that is chrysazin with a methyl substituent at C-3. It has been isolated from Aloe vera and exhibits antiviral and anti-inflammatory activity.
General Description Golden yellow plates or brown powder. Melting point 196°C. Slightly soluble in water. Pale yellow aqueous solutions turn red on addition of alkali. Solutions in concentrated sulfuric acid are red.
Air & Water Reactions Insoluble in water.
Reactivity Profile Chrysophanic acid is incompatible with strong oxidizing agents.
Fire Hazard Flash point data for Chrysophanic acid are not available; however, Chrysophanic acid is probably combustible.