Carboplatin CAS NO.41575-94-4

Carboplatin Basic information

Product Name:	Carboplatin
Synonyms:	1,1-cyclobutanedicarboxylatediammineplatinum(ii);1-cyclobutanedicarboxylato(2-)-o,o’)-diammine((sp-4-2)-platinu;1-cyclobutanedicarboxylato)diammine-(cis-platinum(ii;cbdca;cis-(1,1-cyclobutanedicarboxylato)diammineplatinum(ii);diammine-1,1-cyclobutanedicarboxylateplatinumi;nsc-241240;SP-4-2)-Diammine[1,1-cyclobutanedicar-boxylato-(2-)O,O’]platinum
CAS:	41575-94-4
MF:	C6H12N2O4Pt
MW:	371.25
EINECS:	255-446-0
Product Categories:	Pharmaceutical material and intermeidates;Active Pharmaceutical Ingredients;Antitumors for Research and Experimental Use;Biochemistry;Classes of Metal Compounds;Cyclobutanes & Cyclobutenes;Pt (Platinum) Compounds;Simple 4-Membered Ring Compounds;Transition Metal Compounds;Intermediates & Fine Chemicals;Pharmaceuticals;anti-cancer;metal-ammine complexes;NEMAZINE;Anti cancer;Anti can;Inhibitors
Mol File:	41575-94-4.mol

Carboplatin Chemical Properties

mp	228-230°C
storage temp.	Store at RT
Merck	1822
Stability:	Stable. Incompatible with strong oxidizing agents.
EPA Substance Registry System	Platinum, diammine[1,1-cyclobutanedi( carboxylato-.kappa.O)(2-)]-, (SP-4-2)-(41575-94-4)

Safety Information

MSDS Information

Provider	Language
SigmaAldrich	English
ACROS	English

Carboplatin Usage And Synthesis

Chemical Properties	White Crystals
Usage	anthelmintic
Usage	antitumor agent,
Usage	Analog of Cisplatin with reduced nephrotoxicity. Antineoplastic
Biological Activity	Antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Enhances radiation-induced single-strand DNA breakage and displays lower nephrotoxicity than analog cisplatin (cis-Diaminodichloroplatinum ).