Product Name: N-CARBOBENZOXY-DL-LEUCINE

Synonyms: 2-[[(BENZYLOXY)CARBONYL]AMINO]-4-METHYLPENTANOIC ACID;CARBOBENZYLOXY-DL-LEUCINE;CARBOBENZOXY-DL-LEUCINE;N-CBZ-DL-LEUCINE;N-CARBOBENZOXY-DL-LEUCINE;N-ALPHA-CARBOBENZOXY-DL-LEUCINE;Z-DL-LEUCINE;Z-DL-LEU-OH

CAS: 3588-60-1

MF: C14H19NO4

MW: 265.3

EINECS:

Product Categories: Amino Acids;Amino Acids (N-Protected);Biochemistry;Cbz-Amino Acids

Mol File: 3588-60-1.mol

N-CARBOBENZOXY-DL-LEUCINE Structure

N-CARBOBENZOXY-DL-LEUCINE Chemical Properties

Melting point 54 °C

storage temp. 2-8°C

CAS DataBase Reference 3588-60-1(CAS DataBase Reference)

Safety Information

WGK Germany 3

MSDS Information

Provider Language

SigmaAldrich English

N-CARBOBENZOXY-DL-LEUCINE Usage And Synthesis

Description It is a biologically active amino acid usually used as nutritional supplements, flavour enhancer, and components for preparing pharmaceutical and biochemical products such as amino acid infusion and comprehensive amino acid, hypoglycemic agent, plant growth promoter. Specifically, it is found that ingestion of a high whey protein, leucine-enriched supplement resulted in a larger overall postprandial muscle protein synthesis rate in healthy older people compared with a conventional dairy product.1 Moreover, this substance possesses the most marked anabolic characteristics in acting as a trigger element for the initiation of protein synthesis, thus guaranteeing the healthy human skeleton muscle metabolism.2 In addition, this chemical may be involved in the promotion of plant growth.3

Reference

Luiking, Y. C.; Deutz, N. E. P.; Memelink, R. G.; Verlaan, S.; Wolfe, R. R., Postprandial muscle protein synthesis is higher after a high whey protein, leucine-enriched supplement than after a dairy-like product in healthy older people: a randomized controlled trial. Nutr. J. 2014, 13, 14.

Wilkinson, D. J.; Hossain, T.; Hill, D. S.; Phillips, B. E.; Crossland, H.; Williams, J.; Loughna, P.; Churchward-Venne, T. A.; Breen, L.; Phillips, S. M.; Etheridge, T.; Rathmacher, J. A.; Smith, K.; Szewczyk, N. J.; Atherton, P. J., Effects of leucine and its metabolite -hydroxy--methylbutyrate on human skeletal muscle protein metabolism. J. Physiol.-London 2013, 591, 2911-2923.

Glick, B. R.; Todorovic, B.; Czarny, J.; Cheng, Z. Y.; Duan, J.; McConkey, B., Promotion of plant growth by bacterial ACC deaminase. Crit. Rev. Plant Sci. 2007, 26, 227-242.

Chemical Properties White powder