C3H7NO3 D-Serine 312-84-5 CAS NO.312-84-5

Min.Order: 1 Metric Ton
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Product Details

Keywords

D-Serine
312-84-5
C3H7NO3

Quick Details

ProName: C3H7NO3 D-Serine 312-84-5
CasNo: 312-84-5
Molecular Formula: C3H7NO3
Appearance: Powder
Application: 312-84-5 ...
DeliveryTime: by air
PackAge: Aluminium Foil Bag and Paper Drum
Port: Any port of China
ProductionCapacity: 100 Metric Ton/Day
Purity: 99.5%
Storage: 1MT
Transportation: By Sea/Air/DHL
LimitNum: 1 Metric Ton
Grade: Industrial Grade,Food Grade,Pharma Gra...

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Details

D-Serine Basic information

Description References

Product Name:	D-Serine
Synonyms:	(R)-2-AMINO-3-HYDROXYPROPIONIC ACID;β-Hydroxyalanine;D-SERINE 98.5%;D-Serine,>99%;D-2-Amino-3-Hydroxypropionic;(2R)-2-amino-3-hydroxy-propanoic acid;D-Serin;(R)-2-amino-3-hydroxypropanoic acid
CAS:	312-84-5
MF:	C3H7NO3
MW:	105.09
EINECS:	206-229-4
Product Categories:	Amino Acid Derivatives;Serine [Ser, S];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;Amino Acids;Glutamate receptor;Glutamate;Amines;Inhibitors;Intermediates & Fine Chemicals;Neurochemicals;Pharmaceuticals;Pharmaceutical intermediates;D-Cycloserine intermediate;Lacosamide intermediate
Mol File:	312-84-5.mol

D-Serine Chemical Properties

Melting point	220 °C
alpha	-14.75 º (c=10 2 N HCl)
storage temp.	Store at RT.
solubility	H₂O: 0.1 g/mL, clear, colorless
form	Crystalline Powder
color	White
Water Solubility	346 g/L (20 ºC)
Merck	14,8460
BRN	1721403
InChIKey	MTCFGRXMJLQNBG-UWTATZPHSA-N
CAS DataBase Reference	312-84-5(CAS DataBase Reference)
EPA Substance Registry System	D-Serine(312-84-5)

Safety Information

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	24/25-36-26
WGK Germany	3
RTECS	VT8200000
TSCA	Yes
HS Code	29225000

MSDS Information

Provider	Language
D-Serine	English
SigmaAldrich	English
ACROS	English
ALFA	English

D-Serine Usage And Synthesis

Description	D-serine is the D-form amino acid of the serine, its isomer L-form serine is the component of protein. D-serine is naturally found in the brain, and is a neuromodulator being capable of regulating the activities of neurons. It plays important physiological role in regulating mammalian brain function such as synaptic plasticity and memory. It is also related to the pathophysiology and therapy of several psychiatric and neurological conditions. It can be used for the treatment of cognitive decline, cocaine dependence and schizophrenia. It takes effect through acting as the co-agonist at NDMA receptors, being capable of enhancing the binding of glutamate and NMDA to NDMA receptors.
References	# # Schell, M J, M. E. Molliver, and S. H. Snyder. "D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. " Proceedings of the National Academy of Sciences of the United States of America 92.9(1995):3948-52. mothet, et al. "D-serine is an endogenous ligand for the glycine site of the NMDA receptor." Proceedings of the National Academy of Sciences 69A.5(2000):428–476.
Chemical Properties	White powder
Uses	A proteinogenic amino acids involved in the biosynthesis of purines and pyrimidines. Inhibitor of serine palmitoyltransferase. A neuromodulator.
Definition	ChEBI: The R-enantiomer of serine.