- Product Details
Keywords
- Polyvinylpyrrolidone cross-linked
- C6H9NO
- 99%
Quick Details
- ProName: Polyvinylpyrrolidone cross-linked
- CasNo: 25249-54-1
- Molecular Formula: (C6H9NO)n
- Appearance: powder
- Application: Applications: To assure the effective...
- DeliveryTime: within one month
- PackAge: Aluminium foil bag
- Port: Shanghai Port
- ProductionCapacity: 10 Metric Ton/Day
- Purity: 99.5%
- Storage: Storage features: low-temperature dryi...
- Transportation: By Sea/Air/DHL
- LimitNum: 1 Kilogram
- Grade: Industrial Grade,Pharma Grade,Reagent ...
Superiority
Details
Chemical Name:Crosslinked polyvinlypyrrolidone,Polyvinylpolypyrrolidone USP/EPName:Crospovidone/Crospovidonum INCI/CTFA Name:Insoluble PVP
CAS NO.:25249-54-1;9003-39-8
Molecular Structure:
Properties:
White or cream white,free-flowing powder,hygroscopic,odourless or with characteristic smell,insoluble in water,alkali,acid and all other common solvents,swells rapidly in water but without forming a gel.
Quality Standard:Ph.EP,USP/NF
Product |
PolyKoVidoneTM -XL (Type A) |
PolyKoVidoneTM -10 (Type B) |
Appearance |
White or yellowish-white powder or flakes |
|
Water-soluble substances % max. |
1.0 |
1.0 |
pH Value (1% in water) |
5.0-8.0 |
5.0-8.0 |
Loss on Drying % max |
5.0 |
5.0 |
Sulphate ash % max |
0.1 |
0.1 |
Nitrogen Cotent % |
11.0-12.8 |
11.0-12.8 |
Impurity A(Vinylpyrrolidone) ppm max |
10 |
10 |
Peroxide(As H2O2) ppm max |
400 |
1000 |
Heavy metals ppm max |
10 |
10 |
Partical size (µm), ≥80% |
50-250 |
5-50 |
Applications:
To assure the effectiveness of the medicine,tablets and capsules are required to disintegrate within a certain time,if different adding methods of the disintegrating agent are used,the different disintegrating and dissolution speeds witll be achieved.PolyKoVidone is regarded as the top disintegrating agent thanks to its excellent swelling characteristics after the absoption of moisture.
- Highly efficient disintegrating agent:Makes all excipients swell quickly,effective for wet & dry granulations and direct compression formulations,PolyKoVidone can be added before or after granulation.Its swelling action and disintegration time will be not impacted by wetting or drying.
- Suspension stabilizer:PolyKoVidone acts as a hydrophilic polymer,increasing the viscosity,improving the dispersal capacity,reducing the sedimentation rate of drugs,meanwhile,increasing the redispersal capacity of the solution sediment,suitable for liquid prepara