METERGOLINE Basic information

Product Name: METERGOLINE

Synonyms: n-cbz-[(8β)-1,6-dimethylergolin-8-yl]methylamine;N-Cbz-[(8β)-1,6-Dimethylergolin-8-yl]methylamine, [(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester;[((8beta)-1,6-Dimethylergoline-8-yl)methyl]carbamic acid phenylmethyl ester;Lyserdol;N-[(1,6-Dimethylergolin-8β-yl)methyl]carbamic acid benzyl ester;[(8β)-1,6-Dimethylergolin-8-yl)methyl]carbamicacidphenylmethylester;D-[(4,6,6a,7,8,9,10,10a-Octahydro-4,7-dimethyl-10aalpha-indolo[4,3-fg]quinolin-9beta-yl)methyl]carbamic acid benzyl ester;liserdol

CAS: 17692-51-2

MF: C25H29N3O2

MW: 403.52

EINECS: 241-686-3

Product Categories: Serotonin receptor

Mol File: 17692-51-2.mol

METERGOLINE Structure

METERGOLINE Chemical Properties

Melting point 148-150 °C(lit.)

alpha D28 -7 ±2°

storage temp. −20°C

solubility 0.1 M HCl: 1.4 mg/mL

Merck 13,5962

CAS DataBase Reference 17692-51-2(CAS DataBase Reference)

Safety Information

Hazard Codes Xn

Risk Statements 20/21/22

Safety Statements 36

WGK Germany 3

RTECS FA1070000

Toxicity LD50 in mice (mg/kg): 85 i.p., 430 orally; in rats (mg/kg): >800 orally (Beretta)

MSDS Information

Provider Language

SigmaAldrich English

METERGOLINE Usage And Synthesis

Chemical Properties White Solid

Uses Metergoline is an antagonist at 5-HT1, 5-HT2, and 5-HT7 serotonin receptors. Metergoline is an analgesic; antipyretic.

Biological Activity Antagonist at 5-HT 1 /5-HT 2 with activity at 5-HT 1D . Has moderate affinity for 5-HT 6 and high affinity for 5-HT 7 .