top Betamethasone 21-phosphate disodium CAS NO.151-73-5
- FOB Price: USD: 1.00-1.00 /Kilogram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,T/T,
- Available Specifications:
Best Quality(1-10)Kilogram
- Product Details
Keywords
- Betamethasone 21-phosphate disodium
- high purity Betamethasone 21-phosphate disodium
- factory supply Betamethasone 21-phosphate disodium
Quick Details
- ProName: top Betamethasone 21-phosphate disodiu...
- CasNo: 151-73-5
- Molecular Formula: C22H28FNa2O8P
- Appearance: Colorless to light yellow liquid
- Application: Used in a base-free iridium-catalyzed ...
- DeliveryTime: With about 7-10 days after receipt the...
- PackAge: as you requested
- Port: China main port
- ProductionCapacity: 10 Kilogram/Day
- Purity: 99%
- Storage: room temperature
- Transportation: by courier
- LimitNum: 1 Gram
- Transportation: by courier
Superiority
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:
1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
Our advantage:
1. Higest quality and good package
2.Fast delivery
3.Better payment term
4.Fast response to customer within 6 hours
5.Good business credit in Europe ,US ,Japan ,Korea
Anyway ,if you need any chemicals from China ,Henan Tianfu can help you
Details
Product Name: | Betamethasone 21-phosphate disodium |
Synonyms: | 20-dione,9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-pregna-4-diene-3;21-(dihydrogenphosphate),disodiumsalt;bentelan;Betamethasone Sodium Phosphate (500 mg)K0C3580.993mg/mg(an);Betamethasone Sodium Phosphate (500 mg);Betamethasone 21-pho;(11β,16β)-9-Fluoro-11,17-dihydroxy-16-Methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione SodiuM Salt;9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene -3,20-dione 21-(Dihydrogen Phosphate) SodiuM Salt |
CAS: | 151-73-5 |
MF: | C22H28FNa2O8P |
MW: | 516.4 |
EINECS: | 205-797-0 |
Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Steroids;CELESTONE;Betamethasone;Hormones;Steroid Hormones |
Mol File: | 151-73-5.mol |
Betamethasone 21-phosphate disodium Chemical Properties |
Merck | 14,1180 |
EPA Substance Registry System | Pregna-1,4-diene- 3,20-dione, 9-fluoro-11,17-dihydroxy-16- methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-(151-73-5) |
Safety Information |
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 36 |
WGK Germany | 3 |
RTECS | TU4056500 |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Betamethasone 21-phosphate disodium Usage And Synthesis |
Indications and Usage |
Betamethasone Sodium Phosphate, also called Bentelan, Betnesol, betamethasone phosphate, and celestone phosphate, is an adrenal cortex hormone, an isomer of dexamethasone with the same effects as prednisolone and dexamethasone. It is mainly used against inflammation and allergies. Its effects are the same as those of dexamethasone, and its anti-inflammatory effects are stronger than dexamethasone, prednisone, and cortisone, with fewer side effects. It is used to treat active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukemia, allergic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, pruritis, and comprehensively treat some infections. |
Mechanisms of Action | Betamethasone sodium phosphate has pharmacological effects in treating inflammation, rheumatism, allergies, and immunosuppressive conditions. Its anti-inflammatory effects are stronger than those of dexamethasone, triamcinolone, and hydrocortisone. It can reduce and prevent tissue response to inflammation, partly eliminating non-infectious inflammation caused by fever, redness, and swelling, thereby reducing the presence of swelling. The anti-inflammatory effects of 0.3 mg of betamethasone sodium phosphate are comparable to those of 0.75 mg of dexamethasone, 5 mg of prednisone, or 25 mg of cortisone. Its sodium retention effects are more than a hundred times those of cortisone. In case of primary adrenal hypofunction, together with corticosteroids, it can be used to replace treatment or prevention, or inhibit of cellular immune response, delay allergic reaction, and reduce the extension of the primary immune response, suitable for low renin and low aldosterone syndrome and orthodontic hypotension caused by autonomic neuropathy. |
Contraindications | Not for use by those with a history of serious mental illness, active duodenum, gastric ulcers, recent gastrointestinal anastomosis, serious osteoporosis, pronounced diabetes, or serious high blood pressure, viruses which cannot be treated by antibiotics, bacterial of fungal infection, thrombophlebitis, or infectious skin diseases such as impetigo, tinea corporis, or tinea cruris. |
Category | Toxic |
Toxicity level | Medium |
Acute toxicity | Oral administration - mice LD50: >4500 mg/kg |
Flammability | Flammable; produces toxic fluoride fumes |
Storage and transport | Store in a cool, ventilated, and dry place |
Extinguishing agents | Dry powder, foam, sand, carbon dioxide, mist |
Uses | A Betamethasone |
Uses | antiinflammatory, glucocorticoid |
Uses | Nasal, Ophthalmic, Oral, Parenteral |
Uses | An anti-inflammatory agent |
Definition | ChEBI: An organic sodium salt that is the disodium salt of betamethasone phosphate. |