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Product Name: Flutamide
Synonyms: TIMTEC-BB SBB006930;N1-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE;2-METHYL-N-(4'-NITRO-3'-(TRIFLUOROMETHYL)PHENYL)PROPANAMIDE;2-METHYL-N-(4-NITRO-3-[TRIFLUOROMETHYL]PHENYL)PROPANAMIDE;FLUTAMIDE;AURORA KA-860;2-methyl-4’-nitro-alpha,alpha,alpha-triflouro-m-propionotoluidid;2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)-propanamid
CAS: 13311-84-7
MF: C11H11F3N2O3
MW: 276.21
EINECS: 236-341-9
Product Categories: Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;APIs;Antitumors for Research and Experimental Use;Biochemistry;Amines;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Pharmaceutical raw material;INAPSINE;Hormone Drugs
Mol File: 13311-84-7.mol
Flutamide Structure
Flutamide Chemical Properties
Melting point  112 °C
storage temp.  Store at RT
Merck  4208
CAS DataBase Reference 13311-84-7(CAS DataBase Reference)
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  20/21/22-63-36/37/38
Safety Statements  22-36-36/37/39-27-26
WGK Germany  3
RTECS  UG5700000

Flutamide Usage And Synthesis
Description Flutamide is a kind of synthetic, non-steroidal antiandrogen which is mainly used for the treatment of prostate cancer. It is a kind of toluidine derivative and a nonsteroidal antiandrogen with a similar structure of bicalutamide and nilutamide. The mechanism of its anti-cancer property is through acting as a selective antagonist of the androgen receptor (AR), preventing androgens such as testosterone and its active metabolite dihydrotestosterone from binding to ARs in the prostate gland. This process inhibits androgen-dependent DNA and protein synthesis in the tumor cell. Therefore, it can prevent androgens from stimulating the growth of prostate cancer cells. Moreover, it can also be used for the treatment of hyperandrogenism in women. It is quite effective in alleviating symptoms such as acne, seborrhea, hirsutism and androgenetic alopecia. Finally, it is also useful as a component in the transgender hormone therapy.
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Chemical Properties Light Yellow Solid
Uses neuroleptic
Uses Flutamide is a nonsteroidal antiandrogen drug; antineoplastic (hormonal).
Uses Antiandrogen; antineoplastic (hormonal).