Newblue-CHEM - Nevirapine CAS NO.129618-40-2

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Product Details

Keywords

Nevirapine
129618-40-2
C15H14N4O

Quick Details

ProName: Newblue-CHEM - Nevirapine
CasNo: 129618-40-2
Molecular Formula: C15H14N4O
Appearance: Solid
Application: Organic synthesis
DeliveryTime: PROMPT
PackAge: IN 25kg drums
Port: SHANGHAI
ProductionCapacity: 10 Metric Ton/Month
Purity: 99.0%
Storage: In Room Temperature
Transportation: As per MSDS
LimitNum: 1 Gram
Heavy metal: N/A
Grade: Industrial Grade,Food Grade,Pharma Gra...

Superiority

Henan Newblue Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license.

We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the company is to put quality first and put our customer’s needs first - the satisfaction of our customers is the company's ultimate goal.

Improving product quality and service level is our responsibility, and creating more value for our customer’s is our purpose. We are constantly striving to make Henan Newblue a leading chemical supplier, and hope to create a better future with you.

Details

Nevirapine Basic information

Product Name: Nevirapine

Synonyms: 6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-;5-CYCLOPROPYL-9-METHYL-5,10-DIHYDRO-4,5,6,10-TETRAAZA-DIBENZO[A,D]CYCLOHEPTEN-11-ONE;VIRAMUNE;NEVIRAPINE;Novirapine*;Nevirapine(Nvp);NEVIRAPINE(SUBJECTTOPATENTFREE);11-cyclopropyl-5，11-dihydro-4-methyl-6H-dipyrido[3，2-b:2’，3’-][1，4] diazepin-6-one

CAS: 129618-40-2

MF: C15H14N4O

MW: 266.3

EINECS:

Product Categories: Active Pharmaceutical Ingredients;API;Anti-virals;Inhibitors;Intermediates & Fine Chemicals;Non-nucleoside Reverse Transcriptase;Pharmaceuticals;Other APIs

Mol File: 129618-40-2.mol

Nevirapine Structure

Nevirapine Chemical Properties

Melting point 247°C

Fp 9℃

storage temp. -20°C Freezer

solubility DMSO: ≥22mg/mL

pka 2.8(at 25℃)

color white to tan

Merck 14,6490

CAS DataBase Reference 129618-40-2(CAS DataBase Reference)

Safety Information

Hazard Codes Xi

Risk Statements 36/37/38

Safety Statements 26-36-37/39

RIDADR UN1230 - class 3 - PG 2 - Methanol, solution

RTECS JM5562500

Hazardous Substances Data 129618-40-2(Hazardous Substances Data)

MSDS Information

Provider Language

11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one English

Nevirapine Usage And Synthesis

Chemical Properties Crystalline Solid

Uses amyloidosis therapy

Uses Labelled Nevirapine , a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Antiviral.;Labeled Nevirapine, intended for use as an internal standard for the quantification of Nevirapine by GC- or LC-mass spectrometry.

Uses A potent (IC50=84nM) and selective non-nucleoside inhibitorf HIV-1 reverse transcriptase

Definition ChEBI: A dipyridodiazepine that is 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepine which is substituted by methyl, oxo, and cyclopropyl groups at positions 4, 6, and 11, respectively. A non-nucleoside reverse tr nscriptase inhibitor with activity against HIV-1, it is used in combination with other antiretrovirals for the treatment of HIV infection.

Nevirapine Preparation Products And Raw materials

Raw materials N,N-Dimethylformamide-->2-Chloro-3-amino-4-methyl pyridine-->2-Chloronicotinyl chloride-->NETOBIMIN-->2-Hydroxy-4-methyl-3-nitropyridine

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