Product Name: 2,6-Di-tert-butylphenol
Synonyms: Hitec4701;Isonox 103;Isonox103;Lowinox 001;Phenol, 2,6-bis(t-butyl);Phenol, 2,6-di-tert-butyl-;phenol,2,6-bis(1,1-dimethylethyl)-;Phenol,2,6-di-tert-butyl-
CAS: 128-39-2
MF: C14H22O
MW: 206.32
EINECS: 204-884-0
Product Categories: Industrial/Fine Chemicals;Organic Building Blocks;Oxygen Compounds;Phenols;Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
Mol File: 128-39-2.mol

2,6-Di-tert-butylphenol Chemical Properties
Melting point  34-37 °C(lit.)
Boiling point  253 °C(lit.)
density  0.91
vapor pressure  <0.01 mm Hg ( 20 °C)
refractive index  1.5312
Fp  245 °F
storage temp.  2-8°C
solubility  0.003g/l
pka 12.16±0.40(Predicted)
form  Crystalline Solid
color  White to light yellow
Water Solubility  insoluble
BRN  1841887
Stability: Stable. Incompatible with acid chlorides, acid anhydrides, bases, brass, copper, copper alloys, oxidizing agents.
CAS DataBase Reference 128-39-2(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 2,6-bis(1,1-dimethylethyl)-(128-39-2)
EPA Substance Registry System 2,6-Di-tert-butylphenol (128-39-2)
Safety Information
Hazard Codes  Xn,N,Xi
Risk Statements  22-51/53-52/53-50/53-38
Safety Statements  26-36-61-29-60
RIDADR  UN 3145 8/PG 3
WGK Germany  2
RTECS  SK8265000
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29071900
Hazardous Substances Data 128-39-2(Hazardous Substances Data)

2,6-Di-tert-butylphenol Usage And Synthesis
Chemical Properties white solid
Uses Antioxidant for Gasoline, Jet Fuels, and Electrical Insulating Oils
Uses Antioxidant Intermediate, Pharmaceuticals
General Description Odorless colorless to light yellow solid or liquid. Floats on water. Freezing point is 97°F.
Air & Water Reactions Insoluble in water.
Reactivity Profile Phenols, such as 2,6-Di-tert-butylphenol, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.
Health Hazard Irritates eyes and (on prolonged contact) skin. Ingestion causes irritation of mouth and stomach.
Purification Methods Crystallise the phenol from aqueous EtOH or n-hexane.

Product Name: 2,6-Di-tert-butylphenol
Synonyms: Hitec4701;Isonox 103;Isonox103;Lowinox 001;Phenol, 2,6-bis(t-butyl);Phenol, 2,6-di-tert-butyl-;phenol,2,6-bis(1,1-dimethylethyl)-;Phenol,2,6-di-tert-butyl-
CAS: 128-39-2
MF: C14H22O
MW: 206.32
EINECS: 204-884-0
Product Categories: Industrial/Fine Chemicals;Organic Building Blocks;Oxygen Compounds;Phenols;Building Blocks;C9 to C20+;Chemical Synthesis;Organic Building Blocks;Oxygen Compounds
Mol File: 128-39-2.mol

2,6-Di-tert-butylphenol Chemical Properties
Melting point  34-37 °C(lit.)
Boiling point  253 °C(lit.)
density  0.91
vapor pressure  <0.01 mm Hg ( 20 °C)
refractive index  1.5312
Fp  245 °F
storage temp.  2-8°C
solubility  0.003g/l
pka 12.16±0.40(Predicted)
form  Crystalline Solid
color  White to light yellow
Water Solubility  insoluble
BRN  1841887
Stability: Stable. Incompatible with acid chlorides, acid anhydrides, bases, brass, copper, copper alloys, oxidizing agents.
CAS DataBase Reference 128-39-2(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 2,6-bis(1,1-dimethylethyl)-(128-39-2)
EPA Substance Registry System 2,6-Di-tert-butylphenol (128-39-2)
Safety Information
Hazard Codes  Xn,N,Xi
Risk Statements  22-51/53-52/53-50/53-38
Safety Statements  26-36-61-29-60
RIDADR  UN 3145 8/PG 3
WGK Germany  2
RTECS  SK8265000
TSCA  Yes
HazardClass  9
PackingGroup  III
HS Code  29071900
Hazardous Substances Data 128-39-2(Hazardous Substances Data)

2,6-Di-tert-butylphenol Usage And Synthesis
Chemical Properties white solid
Uses Antioxidant for Gasoline, Jet Fuels, and Electrical Insulating Oils
Uses Antioxidant Intermediate, Pharmaceuticals
General Description Odorless colorless to light yellow solid or liquid. Floats on water. Freezing point is 97°F.
Air & Water Reactions Insoluble in water.
Reactivity Profile Phenols, such as 2,6-Di-tert-butylphenol, do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases. Such heating may initiate polymerization of the organic compound. Phenols are sulfonated very readily (for example, by concentrated sulfuric acid at room temperature). The reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid.
Health Hazard Irritates eyes and (on prolonged contact) skin. Ingestion causes irritation of mouth and stomach.
Purification Methods Crystallise the phenol from aqueous EtOH or n-hexane.