English name: Bispyribac-sodium

English Synonyms: Bispyribac sodium salt, Sodium 2,6-bis (4,6-dimethoxy-2-pyrimidinyloxy) benzoate; dimethoxy-2-pyrimidinyloxy) benzoate; Bispyribac sod; BISPYRIBAC-SODIUM; NOMINEE

CAS number: 125401-92-5

Molecular formula: C19H17N4NaO8

Molecular weight: 452.35

EINECS number:

Related categories: Herbicides; Pesticides; Organic heterocyclic herbicides; Analytical standards; Pesticide residues, veterinary drugs and chemical fertilizers

Mol file: 125401-92-5.mol

Double herbicide

Double grass ether nature

° C 223-224 ° C

Storage conditions 0-6 ° C

Water solubility 73.3 g / l at 20 ºC

CAS Database 125401-92-5 (CAS DataBase Reference)

EPA chemical information Benzoic acid, 2,6-bis [(4,6-dimethoxy-2-pyrimidinyl) oxy] -, sodium salt (125401-92-5)

Double herb ether use and synthesis method

Toxic male rats acute oral LD504111mg / kg, female> 2635mg / kg, rat acute percutaneous LD50> 200mg / kg. Rabbit skin irritation, a slight stimulation of rabbit eyes, no teratogenic, mutagenic effect. Quail oral LD502250mg / kg, large sunfish LC50> 100mg / L (96h), water flea LC50> 100mg / L (48h).

Chemical nature of the pure white powdery solid, mp223 ~ 224 ℃, vapor pressure <5.05 × 10-9Pa (25 ℃), the solubility at 25 ℃: methanol 26.3g / L, acetone 0.043g / L, water 73.3g / L, half-life in water of 1 year (pH 7 to 9), 55 ℃ heat storage 14d does not decompose, pK a3.05.

Uses Pyrimidinyl salicylic acid herbicides, acetolactate inhibitors, act through the biosynthesis of yin Zhi branch chain amino acids for crop rice. Mainly used for direct seeding rice weeding, on the 1st to 7 leaf stage barnyard grass are effective, 3 to 6 leaf stage is particularly effective. On the car forearm grass, mango, sorghum, purple amaranthus, Commelina, melon fur, Shaped sedge, broken Mesa, Chamaeculogyrus, false green purslane, corn grass also have good control effect. This product is stable to most soil and climatic conditions and can be mixed with other pesticides.

Use for the control of paddy grass barnyardgrass and other weeds and broad-leaved weeds in paddy fields, direct seeding, seedling transplanting and throwing seedling field use

Use Bispyribac-sodium is an ultra-efficient, broad-spectrum, low toxicity herbicides, mainly for the control of paddy grass such as barnyardgrass and broadleaf weedy paddy field, seedling, direct seeding, Seedling use.

Production methods diethyl malonate and thiourea as the starting material in the presence of sodium methoxide condensation generated 4,6-dihydroxy-2-pyrimidine thiophenol, and then methylation, chlorination, methoxy 4-dimethoxy-2-methylsulfonyl pyrimidine was obtained through a series of reactions such as alkylation, alkylation and oxidation. Finally, 4,6-dimethoxy-2-methanesulfonylpyrimidine was reacted with 2,6-dihydroxy Benzoic acid in alkaline conditions to give the double herbivorous ether. The overall yield of the six-step reaction was 41% with a content of 95%.