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Scopolamine hydrobromide Basic information
Product Name: Scopolamine hydrobromide
Synonyms: Benzeneacetic acid, a-(hydroxyMethyl)-, (1a,2b,4b,5a,7b)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester, hydrobroMide (1:1), (aS)-;ScopolaMine-d3 HBr 3H2O;Hyosol;Tranaxine;ScopolaMine HBr Trihydrate;Scopolaminehydrobromidetrihydra;(αS)-α-(hydroxymethyl)-benzeneacetic acid-(1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester;( )-Scopolamine hydrobromide hydrate
CAS: 114-49-8
MF: C17H22BrNO4
MW: 384.26
EINECS: 204-050-6
Product Categories: API;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors;Alkaloids;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Acetylcholine receptor
Mol File: 114-49-8.mol
Scopolamine hydrobromide Structure
Scopolamine hydrobromide Chemical Properties
Melting point  195-199 °C (dry matter)(lit.)
alpha  D25 -24 to -26° (c = 5, calculated on anhydrous basis)
storage temp.  Store at RT
solubility  H2O: 50 mg/mL
form  powder
color  white to off-white
CAS DataBase Reference 114-49-8(CAS DataBase Reference)
EPA Substance Registry System Benzeneacetic acid, .alpha.-(hydroxymethyl)-, (1.alpha.,2.beta.,4.beta., 5.alpha.,7.beta.)-9-methyl- 3-oxa-9-azatricyclo[3.3.1. 02,4]non-7-yl ester, hydrobromide, (.alpha.S)-(114-49-8)
Safety Information
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
RIDADR  UN 1544 6.1/PG 1
WGK Germany  3
RTECS  YM4550000
F  3-8

Scopolamine hydrobromide Usage And Synthesis
Chemical Properties Off-White Solid
Uses An acetylcholine antagonist. Used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant
Definition ChEBI: A hydrobromide that is obtained by reaction of scopolamine with hydrogen bromide.
General Description Colorless crystals or white powder or solid. Has no odor. pH (of 5% solution): 4-5.5. Slightly efflorescent in dry air. Bitter, acrid taste.
Air & Water Reactions Sensitive to air, light and moisture. Water soluble.
Reactivity Profile Scopolamine hydrobromide is incompatible with acids, bases and oxidizing agents. .
Fire Hazard Flash point data for Scopolamine hydrobromide are not available; however, Scopolamine hydrobromide is probably combustible.
Biological Activity Non-selective muscarinic antagonist. Widely used clinically to treat motion sickness.