1,2-Dimethoxyethane Basic information

Product Name: 1,2-Dimethoxyethane

Synonyms: 1,2-dimethoxy-ethan;1,2-Ethanediol dimethyl ether;1,2-ethanediol,dimethylether;2,5-Dioxahexane;alpha,beta-Dimethoxyethane;Ansol E-121;Ansul ether 121;ansulether121

CAS: 110-71-4

MF: C4H10O2

MW: 90.12

EINECS: 203-794-9

Product Categories: Amber Glass Bottles;Analytical Reagents;Analytical/Chromatography;CHROMASOLV for HPLC;Chromatography Reagents &;HPLC &;HPLC Grade Solvents (CHROMASOLV);HPLC/UHPLC Solvents (CHROMASOLV);Solvent Bottles;Solvent by Application;Solvent Packaging Options;Solvents;UHPLC Solvents (CHROMASOLV);ACS and Reagent Grade Solvents;Carbon Steel Cans with NPT Threads;ReagentPlus;ReagentPlus Solvent Grade Products;Semi-Bulk Solvents;Polymer chemistry

Mol File: 110-71-4.mol

1,2-Dimethoxyethane Structure

1,2-Dimethoxyethane Chemical Properties

Melting point -69 °C

Boiling point 85 °C(lit.)

density 0.867 g/mL at 25 °C(lit.)

vapor density 3.1 (20 °C, vs air)

vapor pressure 48 mm Hg ( 20 °C)

refractive index n20/D 1.379(lit.)

Fp 32 °F

storage temp. 2-8°C

Water Solubility Miscible

Sensitive Air Sensitive

Merck 14,3224

BRN 1209237

Stability: Stable, but explosive peroxides may form on exposure to air. Test for the presence of peroxides before heating. Avoid heat, light, air. Highly flammable. Store under inert gas.

CAS DataBase Reference 110-71-4(CAS DataBase Reference)

NIST Chemistry Reference Ethane, 1,2-dimethoxy-(110-71-4)

EPA Substance Registry System Ethane, 1,2-dimethoxy-(110-71-4)

Safety Information

Hazard Codes F,T

Risk Statements 60-61-11-19-20-38

Safety Statements 53-45

RIDADR UN 2252 3/PG 2

WGK Germany 1

RTECS KI1451000

F 3-10-23

TSCA Yes

HazardClass 3

PackingGroup II

HS Code 29091900

Hazardous Substances Data 110-71-4(Hazardous Substances Data)

MSDS Information

Provider Language

1,2-Dimethoxyethane English

SigmaAldrich English

ACROS English

ALFA English

1,2-Dimethoxyethane Usage And Synthesis

Chemical Properties Colorless liquid

Usage Solvent commonly employed in organometallic reactions,1 particularly organolithium reactions.2 May also function as a ligand.3

General Description A liquid with a sharp odor. Less dense than water. Flash point 34°F. Mildly toxic by ingestion and inhalation. Severely irritates skin and eyes. Vapors heavier than air. Used to make other chemicals.

Air & Water Reactions Highly flammable. Slightly soluble in water.

Reactivity Profile When the solvent, 1,2-Dimethoxyethane, was poured into a funnel previously used to introduce the lithium aluminum hydride, a fire ignited the funnel, [MCA Case History 1182(1966)].

Health Hazard If ingested causes nausea, vomiting, cramps, weakness, coma.

Fire Hazard Behavior in Fire: Containers may explode in fires.

1,2-Dimethoxyethane Preparation Products And Raw materials

Preparation Products Azetidine-->3-N-Boc-amino-azetidine-->4-(Dicyanomethylene)-2-tert-butyl-6-(1,1,7,7-tetramethyljulolidin-4-yl-vinyl)-4H-pyran-->Pigment Red 122-->3-AMINOBIPHENYL-->Quinolin-2-amine-->TERT-BUTYL 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)ISOINDOLINE-2-CARBOXYLATE-->4-BENZYL-MORPHOLINE-2-CARBOXYLIC ACID-->5-CHLORO-2'-DEOXYURIDINE-->2-Chloro-5-cyano-3-methylpyridine-->Quinacridone-->N,N-DIPHENYLQUINACRIDONE-->3,4-DICHLORO-N-METHYLANILINE-->4-CHLORO-7-METHYLTHIENO[3,2-D]PYRIMIDINE-->4'-BROMO-3'-FLUOROACETANILIDE-->2-PHENYLMALONAMIDE-->2-Bromo-5-hydroxypyridine-->EUROPIUM D-3-TRIFLUOROACETYLCAMPHORATE-->7-METHYL-3,4-DIHYDROTHIENO[3,2-D]PYRIMIDIN-4-ONE-->2-CHLORO-5-IODO-3-METHYLPYRIDINE-->4-CHLORO-1,3-DIMETHYLPYRAZOLO[3,4-B]PYRIDINE-5-CARBOXYLIC ACID-->1-METHYL-1H-INDOLE-5-BORONIC ACID 2,2-DIMETHYL PROPANE DIOL-1,3-CYCLIC ESTER-->THIOPHENE-2,5-DICARBOXYLIC ACID MONOMETHYL ESTER-->N,N'-Dimethylquinacridone-->3-TRIFLUOROACETYL-D-CAMPHOR-->10-UNDECYNOIC ACID-->SabiWhite--->TERT-BUTYL 4-(4-FORMYL-1,3-THIAZOL-2-YL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE-->TERT-BUTYL 4-(5-FORMYL-4-METHYL-1,3-THIAZOL-2-YL)PIPERIDINE-1-CARBOXYLATE-->Beraprost-->TEMAFLOXACIN-->Sarafloxacin-->ETHYL 4-METHOXY-3-OXO-BUTANOATE-->4-Thiazolecarboxylic acid-->1,1,1-TRICHLOROACETONE-->5-FORMYL-2-THIOPHENECARBOXYLIC ACID-->2,3,5,6-Tetrafluorobenzyl alcohol-->2,3,5,6-Tetrafluoro-4-methylbenzyl alcohol

Raw materials Sodium hydroxide-->2-Methoxyethanol