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2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)

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Tetrahydropalmatine Basic information
Description References
Product Name: Tetrahydropalmatine
Synonyms: AKOS 208-04;L-TETRAHYDROPALMATINE;L-TETRAHYDROPALMATINE HCL;DL-TETRAHYDROPALMATINE;TETRAHYDROPALMATINE;ROTUNDINE;ROTUNDIN HYDRATE;ROTUNDINUM
CAS: 10097-84-4
MF: C21H25NO4
MW: 355.43
EINECS:
Product Categories: Alkaloids;Miscellaneous Natural Products;Pharmaceutical intermediate;Plant extracts;chemical reagent;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors
Mol File: 10097-84-4.mol
Tetrahydropalmatine Structure
Tetrahydropalmatine Chemical Properties
CAS DataBase Reference 10097-84-4(CAS DataBase Reference)
Safety Information
Safety Statements  24/25
HS Code  29339900
MSDS Information
Tetrahydropalmatine Usage And Synthesis
Description Tetrahydropalmatine (THP) is an isoquinoline alkaloid found in in several different plant species, mainly in the Corydalis genus (Yan Hu Suo), but also in other plants such as Stephania rotunda (Qian Jin Teng). These plants exhibits analgesic, antinociceptive, anxiolytic, antidepressant, and anti-parasitic activities, and have traditional uses in Chinese herbal medicine. In particular, the levo isomer of THP (l-THP) appears to contribute to many of the therapeutic effects of these herbs. Notably, the dextro isomer of THP has distinct pharmacological actions that include depletion of monoamines and may contribute to the toxicology profile of THP-containing preparations or racemic mixtures of the compound. In addition to serving as an active constituent in traditional Chinese herbal preparations, purified or synthetic l-THP is approved for use and available as Rotundine or Rotundin in China, where l-THP has been used as an analgesic and sedative for more than 40 years.