Newblue CHEM--Suplatast tosilate CAS NO.94055-76-2

Min.Order: 1 Kilogram
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Product Details

Keywords

94055-76-2
Suplatast tosilate
Suplatast tosilate

Quick Details

ProName: Newblue CHEM--Suplatast tosilate
CasNo: 94055-76-2
Molecular Formula: C23H33NO7S2
Appearance: Powder
Application: intermediate
DeliveryTime: depend on yr quantity
PackAge: Aluminium Foil Bag and Paper Drum
Port: shanghai
ProductionCapacity: 100 Kilogram/Month
Purity: 98%
Storage: Room temperature
Transportation: By Sea/Air/DHL
LimitNum: 1 Kilogram
Grade: Industrial Grade

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Details

Product Name: Suplatast tosilate

Synonyms: (2-(4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl)ethyl)dimethylsulfonium p-toluenesulfonate;SUPLATAST TOSILATE;Suplatast tosylate;Suplatast;2-[4-(2-Hydroxy-3-ethoxypropoxy)phenylcarbamoyl]ethyldimethylsulfonium·4-methylbenzenesulfonate;IPD-1151T;S,S-Dimethyl-3-oxo-3-[4-(2-hydroxy-3-ethoxypropoxy)anilino]propane-1-sulfonium·4-methylbenzenesulfonate;[2-[[[4-(2-Hydroxy-3-ethoxypropoxy)phenyl]amino]carbonyl]ethyl]dimethylsulfonium

CAS: 94055-76-2

MF: C23H33NO7S2

MW: 499.64062

EINECS:

Product Categories: API;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;IPD 1151T

Mol File: 94055-76-2.mol

Suplatast tosilate Structure

Suplatast tosilate Chemical Properties

Melting point 84-87°C

storage temp. Store at RT

solubility DMSO: >20mg/mL

color white to off-white

Merck 14,9003

CAS DataBase Reference 94055-76-2(CAS DataBase Reference)

Safety Information

RTECS WR7906000

MSDS Information

Suplatast tosilate Usage And Synthesis

Uses Suplatast Tosylate is an antiallergic drug. Suplatast Tosylate inhibits antigen-induced histamine release from mast cells as well as IgE antibody formation. Suplatast Tosylate suppresses interleukin (IL)-4 release from T cells, however in human peripheral basophils, Suplatast Tosylate inhibited the antigen-induced release of IL-13 but not IL-4.

Uses Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM.

Biological Activity Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN- γ production. Acts as an immunoregulator that suppresses IgE production, eosinophil infiltration and histamine release. Exhibits antiasthmatic, anti-inflammatory and antifibrotic activity in vivo and is orally active.

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