Newblue Alfuzosin hydrochloride CAS NO.81403-68-1

Min.Order: 1 Kilogram
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Product Details

Keywords

Alfuzosin hydrochloride
81403-68-1
TIANFU Alfuzosin hydrochloride

Quick Details

ProName: Newblue Alfuzosin hydrochloride
CasNo: 81403-68-1
Molecular Formula: C19H28ClN5O4
Appearance: white powder
Application: Intermediates
DeliveryTime: as client's demand quantity
PackAge: as requested
Port: SHANGHAI
ProductionCapacity: 10 Metric Ton/Month
Purity: 98% min
Storage: room temperature
Transportation: by sea, by air or by courier
LimitNum: 1 Kilogram

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Details

Alfuzosin hydrochloride Basic information
Product Name: Alfuzosin hydrochloride
Synonyms: alfuzosinehydrochloride;SL-77,499-10;MITTOVAL;N-[3-[(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLYNYL)METHYLAMINO]PROPYL]TETRAHYDRO-2-FURANCARBOXAMIDE;n-[3-[(4-amino-6,7-dimethoxy-2-quinazolynyl)methylamino]propyl]tetrahydro-2-furancarboxamide hydrochloride;XATRAL;URION;UROXANTRAL
CAS: 81403-68-1
MF: C19H28ClN5O4
MW: 425.91
EINECS:
Product Categories: APIs;Antihypertensive;Antihypertensive, Treatment of BPH;Intermediates & Fine Chemicals;Pharmaceuticals;Alfuzosin;Amines;Aromatics;Heterocycles;API;Uroxatral
Mol File: 81403-68-1.mol
Alfuzosin hydrochloride Structure
Alfuzosin hydrochloride Chemical Properties
Melting point 225°C
storage temp. Store at RT
solubility DMSO: >10mg/mL
pka 8.13(at 25℃)
CAS DataBase Reference 81403-68-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xn
Risk Statements 22
RTECS LT9965475
MSDS Information
Alfuzosin hydrochloride Usage And Synthesis
Chemical Properties White to Off-White Solid
Uses a-1- Adrenoceptor antagonist structurally similar to prozosin
Uses Antihypertensor;Alpha 1- adrenergic antagonist
Uses α1-Adrenoceptor antagonist structurally similar to Prozosin. Antihypertensive. Used in treatment of benign prostatic hypertrophy.
Biological Activity Functionally uro-selective α 1 adrenoceptor antagonist that does not discriminate between α 1 subtypes. Inhibits increases in intraurethral pressure caused by phenylephrine-induced contraction by 81% with minor cardiovascular effects. Also relaxes corpus cavernosum tissue (pIC 50 = 7.64) in vitro .
Alfuzosin hydrochloride Preparation Products And Raw materials
Raw materials Quinazoline-->3-Aminopropionitrile-->Alfuzosin

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