English name: 2-CHLOROBENZENESULFONYL ISOCYANATE

English synonym: 2-CHLOROBENZENESULFONYL ISOCYANATE; 2-CHLOROBENZENSULFONYL ISOCYANATE; 2-Chlorophenylsulfonyl Isocyanate; 2-Chlorobenzenesulfonyl; o-chloro benzene sulfonylisocyanate; 2-Chlorobenzenesulfonl isocyanate; 2-Chlorobenzenesulfonyl isocyanate 90%; 2-chloro-N-(oxomethylidene)benzenesulfonamide

CAS No.: 64900-65-8

Molecular formula: C7H4ClNO3S

Molecular weight: 217.63

EINECS number:

Related Categories: Isocyanates; Nitrogen Compounds; Organic Building Blocks; Herbicide Intermediates; Sulfonylurea Herbicides; Pesticide Intermediates; Building Blocks; Chemical Synthesis; Nitrogen Compounds; Organic Building Blocks

Mol file: 64900-65-8.mol

O-chlorobenzenesulfonyl isocyanate

O-chlorobenzenesulfonyl isocyanate

Boiling point 285 °C (lit.)

Density 1.484 g/mL at 25 °C (lit.)

Refractive index n20/D 1.559(lit.)

Flash point >230 °F

CAS database 64900-65-8 (CAS DataBase Reference)

O-chlorobenzenesulfonyl isocyanate use and synthesis

Chemical properties Pure product is a colorless oily liquid, b.p.94 ~ 95 ° C / 40Pa, dissolved in water and air, soluble in acetonitrile, benzene and other solvents.

Use o-Chlorobenzenesulfonyl isocyanate is an intermediate of the sulfonylurea herbicide chlorsulfuron.

Uses Pesticide intermediates.

Production method Using n-butyl isocyanate as a catalyst, using chlorobenzene as a solvent, o-chlorobenzenesulfonamide is reacted with phosgene in a reflux state, and the phosgenation product is exhausted with nitrogen to remove residual phosgene, solvent is removed, and decompression is carried out. The fraction of 130-140 ° C (0.133 kPa) was collected by distillation to obtain o-chlorophenylsulfonyl isocyanate.

Production method The preparation method comprises the steps of: adding xylene and o-chlorobenzenesulfonamide to the reaction kettle, stirring, adding n-butyl isocyanate, heating and refluxing, reacting for 15 min, and then introducing phosgene at 130 ° C for about 6-8 h. After a certain amount of phosgene was introduced, the mixture was stopped, and n-butyl isocyanate and xylene were distilled off under normal pressure, and the residue was o-chlorobenzenesulfonyl isocyanate.