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C31H48O2S2 Probucol 23288-49-5 CAS NO.23288-49-5
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,T/T,
- Product Details
Keywords
- Probucol
- 23288-49-5
- C31H48O2S2
Quick Details
- ProName: C31H48O2S2 Probucol 23288-49-5
- CasNo: 23288-49-5
- Molecular Formula: C31H48O2S2
- Appearance: Powder
- Application: 23288-49-5 ...
- DeliveryTime: by air
- PackAge: Aluminium Foil Bag and Paper Drum
- Port: Any port of China
- ProductionCapacity: 100 Metric Ton/Day
- Purity: 99.5%
- Storage: 1MT
- Transportation: By Sea/Air/DHL
- LimitNum: 1 Metric Ton
- Grade: Industrial Grade,Food Grade,Pharma Gra...
Superiority
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:
1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
Our advantage:
1. Higest quality and good package
2.Fast delivery
3.Better payment term
4.Fast response to customer within 6 hours
5.Good business credit in Europe ,US ,Japan ,Korea
Anyway ,if you need any chemicals from China ,Henan Tianfu can help you
Details
| Probucol Basic information |
| Product Name: | Probucol |
| Synonyms: | PROBUCOL;4,4’-((1-methylethylidene)bis(thio))bis(2,6-bis(1,1-dimethylethyl)-pheno;biphenabid;bisbid;bisphenabid;dh581;4,4'-ISOPROPYLIDINEDITHIO-BIS-(2,6-DI-TERT-BUTYL)PHENOL;4-({1-[(4-hydroxy-3,5-di-t-butylphenyl)thio]-1-methylethyl}thio)-2,6-di-t-butylphenol |
| CAS: | 23288-49-5 |
| MF: | C31H48O2S2 |
| MW: | 516.84 |
| EINECS: | 245-560-9 |
| Product Categories: | Cardiovascular;Aromatics;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API;LORELCO;Isolabel;Cardiovascular APIs |
| Mol File: | 23288-49-5.mol |
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| Probucol Chemical Properties |
| Melting point | 126-128°C |
| storage temp. | Desiccate at +4°C |
| Merck | 14,7755 |
| CAS DataBase Reference | 23288-49-5(CAS DataBase Reference) |
| Safety Information |
| RTECS | AL3705000 |
| MSDS Information |
| Provider | Language |
|---|---|
| 2,2-Propdiyl-bis(4-thio-2,6-di-tert-butylphenol) | English |
| Probucol Usage And Synthesis |
| Description | Probucol is a kind of bis-phenol antioxidant with anti-hyperlipidemic activity. It had been initially developed for the treatment of coronary artery disease. However, its clinical trials were stopped after people found that it could lower the HDL and LDL cholesterol in patients of a history of heart disease. Probucol exerts its effect through accelerating the fractional rate of low-density (LDL) catabolism which is in the final pathway of cholesterol elimination inside the body. It may also inhibit the early stage of cholesterol biosynthesis and dietary cholesterol absorption. |
| References |
# # # |
| Chemical Properties | White Solid |
| Uses | antihyperlipidemic |
| Uses | Probucol is an antilipemic. |
| Uses | anti-hyperlipoproteinemic |
| Uses | An antioxidant, anti-inflammatory, and hypocholesterolemic agent which inhibits atherogenesis in murine models. |
| Definition | ChEBI: A dithioketal that is propane-2,2-dithiol in which the hydrogens attached to both sulfur atoms are replaced by 3,5-di-tert-butyl-4-hydroxyphenyl groups. An anticholesteremic drug with antioxidant and anti-inflammatory properties, it is used to treat high l vels of cholesterol in blood. |
| Biological Activity | Antioxidant, anti-inflammatory and hypocholesterolemic agent. Inhibits atherogenesis in genetically hypercholesterolemic rabbits (Watanabe) and attenuates ischemia/reperfusion-induced cardiomyocyte apoptosis. |
| Probucol Preparation Products And Raw materials |
| Raw materials | Sodium bicarbonate-->Disulfur dichloride-->2,6-Di-tert-butylphenol-->2,6-Di-tert-butyl-4-mercaptophenol |