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C26H27N5O2.ClH VILAZODONE 163521-12-8 CAS NO.163521-12-8
- Min.Order: 1 Metric Ton
- Payment Terms: L/C,T/T,
- Product Details
Keywords
- VILAZODONE
- 163521-12-8
- C26H27N5O2.ClH
Quick Details
- ProName: C26H27N5O2.ClH VILAZODONE 163521-12-...
- CasNo: 163521-12-8
- Molecular Formula: C26H27N5O2.ClH
- Appearance: Powder
- Application: 163521-12-8 ...
- DeliveryTime: by air
- PackAge: Aluminium Foil Bag and Paper Drum
- Port: Any port of China
- ProductionCapacity: 100 Metric Ton/Day
- Purity: 99.5%
- Storage: 1MT
- Transportation: By Sea/Air/DHL
- LimitNum: 1 Metric Ton
- Grade: Industrial Grade,Food Grade,Pharma Gra...
Superiority
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below:
1.Noble Metal Catalysts (Pt.Pd...)
2.Organic Phosphine Ligands (Tert-butyl-phosphine.Cyclohexyl-phosphine...)
3.OLED intermediates (Fluorene,Carbazole,Boric acid...)
4.Customs Synthesis
Our advantage:
1. Higest quality and good package
2.Fast delivery
3.Better payment term
4.Fast response to customer within 6 hours
5.Good business credit in Europe ,US ,Japan ,Korea
Anyway ,if you need any chemicals from China ,Henan Tianfu can help you
Details
| VILAZODONE Basic information |
| Product Name: | VILAZODONE |
| Synonyms: | 5-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide;2-BenzofurancarboxaMide,5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-;Vilazodonei;Vilazodone 5-[4-[4-(5-Cyanoindol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide;5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide;Vilazodone, >=98%;Vilozodone;VILAZODONE |
| CAS: | 163521-12-8 |
| MF: | C26H27N5O2.ClH |
| MW: | 477.993 |
| EINECS: | |
| Product Categories: | Other APIs;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 163521-12-8.mol |
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| VILAZODONE Chemical Properties |
| Melting point | 203-205°C |
| storage temp. | Refrigerator |
| Safety Information |
| VILAZODONE Usage And Synthesis |
| Description | Vilazodone is a kind of serotonergic antidepressant developed by Merck KGaA Company. It is a novel compound with high affinity and selectivity for the 5-hydroxytrptamine (5-HT) transporter and 5-HT (1A) receptors. It is indicated for the treatment of major depressive disorder (MDD). It is can be used as an alternative drugs for other kind of antidepressant classes drugs that can’t be tolerated by patients. As a selective serotonin reuptake inhibitor, vilazodone can prevent the serotonin from re-entering into cell bodies, therefore making it remain longer inside the synapse. Moreover, it has a high selectivity for the serotonin-1A receptor, taking effect as a partial agonist that can simulate the production of serotonin. These effects result in increased serotonin in the synaptic cleft. This effect is related to the antidepressant effect of vilazodone in vivo. |
| References |
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| Chemical Properties | Light Yellow Solid |
| Uses | Labelled analogue of Vilazodone |
| Uses | An inhibitor of ST and activator of SR-1A |
| Uses | It is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation for the treatment of major depression. |
| Definition | ChEBI: A 1-benzofuran that is 5-(piperazin-1-yl}-1-benzofuran-2-carboxamide having a (5-cyanoindol-3-yl)butyl group attached at position N-4 on the piperazine ring. Used for the treatment of major depressive disorder. |
