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Newblue-CHEM - Olmesartan Medoxomil CAS NO.144689-63-4
- FOB Price: USD: 1,000.00-1,000.00 /Kilogram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
1(1-100)Kilogram
- Product Details
Keywords
- Olmesartan Medoxomil
- 144689-63-4
- C24H26N6O3
Quick Details
- ProName: Newblue-CHEM - Olmesartan Medoxomil
- CasNo: 144689-63-4
- Molecular Formula: C24H26N6O3
- Appearance: Solid
- Application: Organic synthesis
- DeliveryTime: PROMPT
- PackAge: IN 25kg drums
- Port: SHANGHAI
- ProductionCapacity: 10 Metric Ton/Month
- Purity: 99.0%
- Storage: In Room Temperature
- Transportation: As per MSDS
- LimitNum: 1 Gram
- Heavy metal: N/A
- Grade: Industrial Grade,Food Grade,Pharma Gra...
Superiority
Henan Newblue Chemical Co., Ltd. is located in Zhengzhou High-tech Development Zone with import and export license.
We passed ISO 9001:2008 in 2009, and won "High-tech Enterprise" by provincial government in 2013.The objective of the company is to put quality first and put our customer’s needs first - the satisfaction of our customers is the company's ultimate goal.
Improving product quality and service level is our responsibility, and creating more value for our customer’s is our purpose. We are constantly striving to make Henan Newblue a leading chemical supplier, and hope to create a better future with you.
Details
Olmesartan Medoxomil Basic information
Product Name: Olmesartan Medoxomil
Synonyms: (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl] 4-yl)methyl)-4-(;OMST;OlMesartan MedoxoMil SynoyM:4-(1-Hydroxy-1-Methylethyl)-2-propyl-1-[[2'-(1H-tetazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-1H-iMidazole-5-carboxylic acid (5-Methyl-2-oxo-1,3-dioxol-4-yl)Methyl ester;1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester;Olmesartan medoxomil for system suitability;Olmesartan MedoxomiI;Olmesartan Medoxomi;(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2'-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-4-(2-hyd
CAS: 144689-63-4
MF: C24H26N6O3
MW: 446.5
EINECS:
Product Categories: API;OMNICEF;Cardiovascular APIs;Active Pharmaceutical Ingredients;Aromatics;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Olmesartan;Inhibitor
Mol File: 144689-63-4.mol
Olmesartan Medoxomil Structure
Olmesartan Medoxomil Chemical Properties
Melting point 180°C
Fp 180°C
storage temp. -20°C Freezer
solubility DMSO: soluble20mg/mL, clear
color white to beige
Decomposition 180 ºC
CAS DataBase Reference 144689-63-4(CAS DataBase Reference)
Safety Information
RTECS NI4014200
MSDS Information
Olmesartan Medoxomil Usage And Synthesis
Chemical Properties White to off-white crystalline powder
Uses Olmesartan medoxomil is an angiotensin II receptor antagonist used to treat high blood pressure. Olmesartan works by blocking the binding of angiotensin II to the AT1 receptors in vascular muscle. By blocking the binding rather than the synthesis of angiotensin II, olmesartan inhibits the negative regulatory feedback on renin secretion.
Olmesartan medoxomil is a pro-drug that is de-esterified to the active metabolite, olmesartan. Olmesartan has a dual method of elimination, with about 60% eliminated by the liver and the remainder by the kidney. In situations of impaired renal or hepatic function, the alternative excretion pathway can compensate for the compromised one. Olmesartan is not metabolized by the cytochrome P450 enzyme system and therefore has a low potential for metabolic drug interactions, a feature that may be of importance when treating patients on multiple drug regimens, such as the elderly. Olmesartan is well tolerated and has an excellent safety profile that is comparable to that of placebo. In addition, olmesartan provides 24-h blood pressure control with a once-daily dosing. In head-to-head studies, olmesartan delivered superior blood pressure reduction when compared with other angiotensin-II receptor antagonists at their recommended doses.
Uses An angiotensin II receptor antagonist. Used as an anti-hypertensive
Olmesartan Medoxomil Preparation Products And Raw materials